Scott Rogers, Ph.D.

Professor of Neurobiology and Anatomy (b. 1955); B.S., M.S., 1979, Utah State University; Ph.D. 1986, University of Utah; Post-Doctorate, 1986-1991, The Salk Institute for Biological Sciences. Email: Office Phone: 801-585-6339

We are interested in the molecular mechanisms of neuro-immune interactions. To examine these issues, our focus is on problems related to inflammatory processes in the brain and how interactions between the immune system and the nervous system impact upon the expression and function of neurotransmitter receptors. Basically two lines of research are emphasized. First, we are interested in autoimmune-related mechanisms that underlie severe neurological diseases. Second, we examine the relationship between changes in neurotransmitter receptor expression and function in the aging brain.

Search Pubmed for Scott Roger's lab publications

Selected Studies Exploring Neuro-Immune Interactions in Disease

Gahring, L. C., and S. W. Rogers. (1998) Autoimmunity to glutamate receptors in Rasmussen's encephalitis: A rare finding or the tip of an iceberg? The Neuroscientist 4:373-379.

Carlson, N. G., L. C. Gahring, R. E. Twyman, and S. W. Rogers. (1997) Identification of amino acids in the glutamate receptor subunit, GluR3, important for antibody-binding and receptor activation. J. Biol. Chem. 272:11295-11301.

Twyman, R. E., L. C. Gahring, J. Speiss, and S. W. Rogers. (1995) Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site. Neuron 14:755-762.

Rogers, S. W., I. Andrews, L. C. Gahring, T. Whisenand, T. Hughes, K. Cauley, S. Heineman, and J. O. McNamara. (1994) Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis. Science 265:648.

Selected Studies Describing Neuro-Immune Interactions in Aging and Mechanisms of Neurodegeneration:

Rogers, S. W., N. G. Carlson, W. A. Wieggel, J. Chen, A. Bacchi, S. W. Rogers, and L. C. Gahring. (1999) Inflammatory cytokines IL-1alpha, IL-1beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways. J Immunol. 163:3963-3968.

Carlson, N. G., A. Bacchi, S. W. Rogers, and L. C. Gahring. (1998) Nicotine blocks TNFalpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway. J. Neurobiol. 35:29-36.

Rogers, S. W., L. C. Gahring, A. C. Collins, and M. Marks. (1998) Age-Related changes In neuronal nicotinic acetylcholine receptor subunit Alpha-4 expression are modified by long-term nicotine administration. J. Neurosci. 18:4825-4832.

The Neuro-Biology of Extinct Species (A Hobby)

Rogers, S. W. (1999) Allosaurus, crocodiles and birds: Evolutionary clues from spiral computed tomography of an endocast. The Anatomical Record (New Anat.) 257:162-173.

Rogers, S. W. Exploring dinosaur neuro-paleobiology: Computed tomography scanning and analysis of an Allosaurus fragilis endocast. (1998) Neuron 21:673-679.